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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCT2 All Species: 42.73
Human Site: T406 Identified Species: 62.67
UniProt: P78371 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78371 NP_006422.1 535 57488 T406 Q T V K D S R T V Y G G G C S
Chimpanzee Pan troglodytes XP_509216 616 65438 T487 Q T V K D S R T V Y G G G C S
Rhesus Macaque Macaca mulatta XP_001108460 589 62930 T460 Q T V K D S R T V Y G G G C S
Dog Lupus familis XP_531675 535 57413 T406 Q T V K D S R T V Y G G G C S
Cat Felis silvestris
Mouse Mus musculus P80314 535 57459 T406 Q T V K D P R T V Y G G G C S
Rat Rattus norvegicus Q5XIM9 535 57440 T406 Q T V K D P R T V Y G G G C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511892 563 60802 T434 Q T V K D S R T V Y G G G C S
Chicken Gallus gallus Q5ZJK8 553 60330 V405 R A I K N D S V V A G G G A I
Frog Xenopus laevis NP_001080388 535 57647 T406 Q T V K D T R T V Y G G G C S
Zebra Danio Brachydanio rerio NP_958863 535 57743 T406 Q T V K E T R T V Y G G G C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12613 557 59538 V411 R V L E S K K V V A G G G C V
Honey Bee Apis mellifera XP_393300 534 57884 I405 A T V R E S R I V Y G G G C S
Nematode Worm Caenorhab. elegans P47207 529 56956 T400 T H V K E S K T V A G A G A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326179 527 57189 V401 Q T V N D S R V L L G G G W P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28769 545 59211 V411 R T L E S N T V V A G G G A V
Baker's Yeast Sacchar. cerevisiae P39076 527 57185 T400 Q T T K E T R T V L G G G C A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.8 90.8 98.3 N.A. 97.5 97.7 N.A. 91.3 34 90.2 87.4 N.A. 34.8 73.2 66.7 N.A.
Protein Similarity: 100 86.8 90.8 100 N.A. 99.2 99 N.A. 93.4 54 96 94.2 N.A. 57 86.9 80 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 33.3 93.3 86.6 N.A. 33.3 73.3 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 53.3 100 100 N.A. 60 86.6 66.6 N.A.
Percent
Protein Identity: 68 N.A. N.A. 34.6 64.8 N.A.
Protein Similarity: 82.2 N.A. N.A. 56.7 79.8 N.A.
P-Site Identity: 60 N.A. N.A. 33.3 66.6 N.A.
P-Site Similarity: 66.6 N.A. N.A. 60 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 0 0 0 25 0 7 0 19 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % C
% Asp: 0 0 0 0 57 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 13 25 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 100 94 100 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 7 % I
% Lys: 0 0 0 75 0 7 13 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 13 0 0 0 0 0 7 13 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 7 % P
% Gln: 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 19 0 0 7 0 0 75 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 13 50 7 0 0 0 0 0 0 0 69 % S
% Thr: 7 82 7 0 0 19 7 69 0 0 0 0 0 0 0 % T
% Val: 0 7 75 0 0 0 0 25 94 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _